1 00:00:02,510 --> 00:00:05,680 [Music] 2 00:00:10,810 --> 00:00:27,119 [Music] 3 00:00:27,119 --> 00:00:29,320 for thousands of years the struggle 4 00:00:29,320 --> 00:00:33,359 for survival requires the search for 5 00:00:36,320 --> 00:00:39,320 food throughout the seasons 6 00:00:39,320 --> 00:00:40,879 resources could be scarce 7 00:00:40,879 --> 00:00:43,840 gathering and hunting were going well 8 00:00:43,840 --> 00:00:46,719 often the stomach 9 00:00:47,200 --> 00:00:50,559 [Music] 10 00:00:50,559 --> 00:00:53,640 empty then the diets gave way to 11 00:00:53,640 --> 00:00:57,399 a new golden age 12 00:01:04,500 --> 00:01:22,059 [Music] 13 00:01:22,400 --> 00:01:25,280 this idea that the abundance of food 14 00:01:25,280 --> 00:01:27,520 so you can open your fridge 15 00:01:27,520 --> 00:01:29,320 and and eat at any time of the day 16 00:01:29,320 --> 00:01:31,680 day or anytime is 17 00:01:31,680 --> 00:01:34,920 completely in discordance with the 18 00:01:34,920 --> 00:01:37,119 way we were 19 00:01:37,119 --> 00:01:39,240 made we are programmed by 20 00:01:39,240 --> 00:01:40,320 our 21 00:01:40,320 --> 00:01:43,280 genetics to make us feel our best 22 00:01:43,280 --> 00:01:46,079 when we fast we eat fast 23 00:01:46,079 --> 00:01:50,360 let's eat it's the survival program of 24 00:01:54,560 --> 00:01:57,240 evolution would we be drawn by 25 00:01:57,240 --> 00:02:00,439 evolution to fast 26 00:02:00,439 --> 00:02:03,119 reconnected with this capacity would he have 27 00:02:03,119 --> 00:02:06,600 beneficial effects on our 28 00:02:07,679 --> 00:02:10,160 health is the Paris of 29 00:02:10,160 --> 00:02:13,920 Stéphane urban IT consultant 30 00:02:13,920 --> 00:02:17,160 sedentary Stéphane runs after the 31 00:02:17,160 --> 00:02:21,130 time and never disdains a good 32 00:02:21,130 --> 00:02:25,599 [Music] 33 00:02:25,599 --> 00:02:28,920 meal but at 50 years after alert 34 00:02:28,920 --> 00:02:31,120 medical 35 00:02:31,120 --> 00:02:32,800 he made a decision 36 00:02:32,800 --> 00:02:37,959 radical stphane leaves for treatment 37 00:02:38,080 --> 00:02:40,360 young today the practice is 38 00:02:40,360 --> 00:02:41,360 become 39 00:02:41,360 --> 00:02:44,440 trend subject of controversy also and 40 00:02:44,440 --> 00:02:46,200 of 41 00:02:46,200 --> 00:02:51,560 passion now fashion is the I 42 00:03:01,800 --> 00:03:03,840 simple fashion effect without foundation 43 00:03:03,840 --> 00:03:07,200 scientific or even dangerous or true 44 00:03:07,200 --> 00:03:09,159 solution to relieve and heal 45 00:03:09,159 --> 00:03:12,080 words created by our mode of 46 00:03:12,080 --> 00:03:14,959 life for ten years 47 00:03:14,959 --> 00:03:16,760 more and more researchers 48 00:03:16,760 --> 00:03:18,640 explores the therapeutic effects of 49 00:03:18,640 --> 00:03:21,599 fasting and reveals new mechanisms 50 00:03:21,599 --> 00:03:23,720 of the functioning of the body 51 00:03:23,720 --> 00:03:26,000 human it attacks diseases 52 00:03:26,000 --> 00:03:27,799 chronic compensated 53 00:03:27,799 --> 00:03:30,200 irreversible pushes the limits of 54 00:03:30,200 --> 00:03:32,560 aging and revolutionizes 55 00:03:32,560 --> 00:03:36,080 design of our rhythms of 56 00:03:36,400 --> 00:03:39,080 life is the last 10 years thanks to 57 00:03:39,080 --> 00:03:41,159 numerous randomized clinical studies 58 00:03:41,159 --> 00:03:42,599 we have seen more progress in the 59 00:03:42,599 --> 00:03:44,720 research on fasting that probably 60 00:03:44,720 --> 00:03:47,730 over the last 2000 61 00:03:47,730 --> 00:03:54,020 [Music] 62 00:03:55,319 --> 00:03:58,720 years worried about his health stphan has 63 00:03:58,720 --> 00:04:02,360 decided to fast for 2 64 00:04:02,720 --> 00:04:08,000 weeks I'm a little apprehensive because 65 00:04:08,000 --> 00:04:10,480 it's it's a Paris it's quite long 66 00:04:10,480 --> 00:04:14,280 I hope to last until the end 67 00:04:14,280 --> 00:04:15,359 not too much 68 00:04:15,359 --> 00:04:19,238 difficult that's it 69 00:04:24,919 --> 00:04:27,240 shakes up the young therapeutic netant 70 00:04:27,240 --> 00:04:28,720 not recognized in 71 00:04:28,720 --> 00:04:31,000 France cross a border to 72 00:04:31,000 --> 00:04:33,800 fast under supervision 73 00:04:33,800 --> 00:04:36,960 medical direction to Germany in a 74 00:04:36,960 --> 00:04:39,280 clinic 75 00:04:43,280 --> 00:04:46,120 private you put yourself on the Valance 76 00:04:46,120 --> 00:04:49,759 very good and the weight 77 00:04:50,100 --> 00:04:51,440 [Music] 78 00:04:51,440 --> 00:04:54,479 966 before being allowed to fast 79 00:04:54,479 --> 00:04:56,440 Stéphane must submit to a series 80 00:04:56,440 --> 00:05:00,080 medical checks 81 00:05:00,720 --> 00:05:03,199 if he 82 00:05:03,960 --> 00:05:06,320 please then I have the results 83 00:05:06,320 --> 00:05:08,720 laboratory that I wanted to share with 84 00:05:08,720 --> 00:05:11,360 you analysis of blood results 85 00:05:11,360 --> 00:05:13,240 brings bad news from 86 00:05:13,240 --> 00:05:15,199 from there there are the parameters for the 87 00:05:15,199 --> 00:05:18,440 sugar we see that fasting sugar is 88 00:05:18,440 --> 00:05:21,680 high and we also see that insulin at 89 00:05:21,680 --> 00:05:24,240 young is high and that is typical for 90 00:05:24,240 --> 00:05:25,720 a 91 00:05:25,720 --> 00:05:27,600 insulin resistance I don't know if you 92 00:05:27,600 --> 00:05:30,800 have heard of it is what we have before 93 00:05:30,800 --> 00:05:33,360 to have diabetes okay so it's 94 00:05:33,360 --> 00:05:34,840 a 95 00:05:34,840 --> 00:05:37,240 prediabetes the doctor also offers a 96 00:05:37,240 --> 00:05:40,800 liver examination with 112 rounds of 97 00:05:40,800 --> 00:05:43,319 size stéphane is a good candidate for 98 00:05:43,319 --> 00:05:46,800 hepatic steatosis i.e. FO 99 00:05:46,800 --> 00:05:49,960 fatty this disease invisible to the naked eye 100 00:05:49,960 --> 00:05:55,759 can develop into cirotic fibrosis or even into 101 00:05:56,280 --> 00:06:01,280 Cancer now we're doing the Mure 102 00:06:04,560 --> 00:06:07,280 parameters measure the fat in 103 00:06:07,280 --> 00:06:09,639 your 104 00:06:10,639 --> 00:06:15,039 FO it's really estess of 300 so 105 00:06:15,039 --> 00:06:17,120 we can say that it is a 106 00:06:17,120 --> 00:06:20,120 FO ser a level 107 00:06:20,120 --> 00:06:22,360 normal which is not appreciated it is beneath 108 00:06:22,360 --> 00:06:24,199 of 250 109 00:06:24,199 --> 00:06:27,479 240 you are at 307 it is therefore a FO gr 110 00:06:27,479 --> 00:06:30,479 advanced 111 00:06:31,960 --> 00:06:33,440 I 112 00:06:33,440 --> 00:06:35,800 understand Stéphane therefore suffers from a 113 00:06:35,800 --> 00:06:38,120 classic metabolic syndrome with 114 00:06:38,120 --> 00:06:41,360 prediabetes and steatosis of the 115 00:06:41,360 --> 00:06:44,440 liver his 14 day fast 116 00:06:44,440 --> 00:06:48,160 will he correct his mess 117 00:06:48,319 --> 00:06:52,280 metabolic here the cures last one to 3 118 00:06:52,280 --> 00:06:55,960 weeks the protocol is simple 250 119 00:06:55,960 --> 00:06:58,560 calories per day approximately in the form of 120 00:06:58,560 --> 00:07:01,840 broth and lots 121 00:07:01,840 --> 00:07:06,800 of water there is approximately since 1953 where the 122 00:07:06,800 --> 00:07:08,560 first clinic was 123 00:07:08,560 --> 00:07:12,400 created nearly half a million people 124 00:07:12,400 --> 00:07:15,120 who came to fast under supervision 125 00:07:15,120 --> 00:07:17,400 medical in general for reasons 126 00:07:17,400 --> 00:07:19,120 metabolic i.e. obesity 127 00:07:19,120 --> 00:07:21,759 hypertension fatty liver disorder 128 00:07:21,759 --> 00:07:22,879 of the 129 00:07:22,879 --> 00:07:24,879 blood sugar but also for diseases 130 00:07:24,879 --> 00:07:27,000 chronic inflammatory cases typically 131 00:07:27,000 --> 00:07:28,840 arthritis polyarthritis diseases 132 00:07:28,840 --> 00:07:30,440 joints 133 00:07:30,440 --> 00:07:32,479 allergies asthma anything that 134 00:07:32,479 --> 00:07:34,919 is 135 00:07:37,720 --> 00:07:39,360 inflammatory we have done a lot 136 00:07:39,360 --> 00:07:41,080 of scientific studies first for 137 00:07:41,080 --> 00:07:44,240 to show the safety of fasting we 138 00:07:44,240 --> 00:07:46,280 seen on thousands of people it 139 00:07:46,280 --> 00:07:48,960 there is no negative effect or there are 140 00:07:48,960 --> 00:07:51,199 mild symptoms like fatigue soreness 141 00:07:51,199 --> 00:07:53,560 head but that the young man really didn't have 142 00:07:53,560 --> 00:07:57,280 no adverse effects on the 143 00:07:57,280 --> 00:08:00,080 health for ten years under 144 00:08:00,080 --> 00:08:02,639 the impulse of doctor vilelmi of Toledo 145 00:08:02,639 --> 00:08:04,240 the clinic conducts research to 146 00:08:04,240 --> 00:08:05,919 scientifically document the 147 00:08:05,919 --> 00:08:06,930 observations 148 00:08:06,930 --> 00:08:08,280 [Music] 149 00:08:08,280 --> 00:08:10,520 clinical studies among the studies that we have 150 00:08:10,520 --> 00:08:12,720 carried out, it is true that we addressed 151 00:08:12,720 --> 00:08:16,000 dozens of topics on hypertension 152 00:08:16,000 --> 00:08:17,479 the rates of 153 00:08:17,479 --> 00:08:20,199 cholesterol the first for me is 154 00:08:20,199 --> 00:08:22,240 fatty liver disease because someone 155 00:08:22,240 --> 00:08:24,360 who has suffered from fatty liver will see his 156 00:08:24,360 --> 00:08:26,360 treating doctor the doctor will tell him 157 00:08:26,360 --> 00:08:27,919 there is no solution because there is 158 00:08:27,919 --> 00:08:29,980 no medication for fatty liver 159 00:08:29,980 --> 00:08:33,269 [Music] 160 00:08:34,399 --> 00:08:36,799 but how can the young person relieve 161 00:08:36,799 --> 00:08:39,640 see 162 00:08:40,360 --> 00:08:42,760 cure lack of food during 163 00:08:42,760 --> 00:08:45,720 more than approximately 12 hours creates stress which 164 00:08:45,720 --> 00:08:49,120 triggers several mechanisms 165 00:08:49,120 --> 00:08:52,080 adaptation the first amplifies a 166 00:08:52,080 --> 00:08:55,720 essential function of our cells 167 00:08:55,720 --> 00:08:58,519 autophagy literally eats itself 168 00:08:58,519 --> 00:09:01,440 oneself 169 00:09:02,440 --> 00:09:04,959 deprived of external nutrients our 170 00:09:04,959 --> 00:09:07,800 LAN cells a recycling operation 171 00:09:07,800 --> 00:09:10,800 to continue to 172 00:09:12,399 --> 00:09:14,839 function we humans are 173 00:09:14,839 --> 00:09:17,279 like the forest 174 00:09:17,279 --> 00:09:19,959 ecosystem it is an ecosystem where it is 175 00:09:19,959 --> 00:09:22,560 energy question 176 00:09:22,560 --> 00:09:25,279 recycling if I want to make a fire it will 177 00:09:25,279 --> 00:09:30,200 you need wood and it produces energy 178 00:09:32,040 --> 00:09:33,959 and as we choose old wood for 179 00:09:33,959 --> 00:09:36,640 make our cells fire 180 00:09:36,640 --> 00:09:38,800 select damaged components 181 00:09:38,800 --> 00:09:40,279 which accumulate when they 182 00:09:40,279 --> 00:09:42,720 get old then she recycles them 183 00:09:42,720 --> 00:09:44,760 thus providing energy and 184 00:09:44,760 --> 00:09:47,279 components all 185 00:09:47,279 --> 00:09:50,240 nine crucial benefit of the operation 186 00:09:50,240 --> 00:09:52,560 they eliminate waste this debris 187 00:09:52,560 --> 00:09:54,360 cells that create inflammation 188 00:09:54,360 --> 00:09:56,600 in the body and promotes diseases 189 00:09:56,600 --> 00:09:59,440 chronicles 190 00:09:59,440 --> 00:10:01,279 the discovery of the genes which control 191 00:10:01,279 --> 00:10:04,320 autophagy earned professor ozumi 192 00:10:04,320 --> 00:10:07,470 the Nobel Prize in Medicine in 193 00:10:07,470 --> 00:10:09,399 [Music] 194 00:10:09,399 --> 00:10:12,560 2016 and what's exciting is that 195 00:10:12,560 --> 00:10:14,640 the most powerful method 196 00:10:14,640 --> 00:10:16,880 strong to stimulate autophagy it is 197 00:10:16,880 --> 00:10:18,640 the 198 00:10:18,640 --> 00:10:22,279 fast this recycling this energy is 199 00:10:22,279 --> 00:10:24,640 an essential intervention in our 200 00:10:24,640 --> 00:10:28,320 organism it's like an operation without 201 00:10:28,320 --> 00:10:30,040 scalpel that's why very 202 00:10:30,040 --> 00:10:34,279 many diseases are improved by 203 00:10:34,920 --> 00:10:38,279 fasting Andre Michelson leads a service 204 00:10:38,279 --> 00:10:40,639 of integrative medicine in connection with 205 00:10:40,639 --> 00:10:43,079 the Charité hospital in 206 00:10:43,079 --> 00:10:45,680 Berlin is one of six hospitals 207 00:10:45,680 --> 00:10:49,880 public which offers fasting cures in 208 00:10:53,680 --> 00:10:55,839 Germany when prescribed 209 00:10:55,839 --> 00:11:00,519 by medical cures are reimbursed 210 00:11:03,440 --> 00:11:06,480 Mo the young attracts a growing number 211 00:11:06,480 --> 00:11:08,800 of patients with chronic illness 212 00:11:08,800 --> 00:11:12,079 that modern medicine at best relieves 213 00:11:12,079 --> 00:11:14,279 but does not heal 214 00:11:14,279 --> 00:11:17,839 not und sounds wie geht viel viel besser 215 00:11:17,839 --> 00:11:20,959 als ich dachte also wunderbar eigentlich 216 00:11:20,959 --> 00:11:24,440 schmerzen sind fast ganz Weg bisschen 217 00:11:24,440 --> 00:11:26,959 und so nach sport dann merke ich wieder 218 00:11:26,959 --> 00:11:31,240 anfängt zuun aber 219 00:11:37,279 --> 00:11:40,279 accpagn here around 30 to 40,000 patients 220 00:11:40,279 --> 00:11:42,680 with the 221 00:11:43,760 --> 00:11:46,120 fast there are really a lot of 222 00:11:46,120 --> 00:11:48,440 change in the last 10 223 00:11:48,440 --> 00:11:50,959 years I think the most important step 224 00:11:50,959 --> 00:11:52,920 important that we have crossed is 225 00:11:52,920 --> 00:11:55,360 that of the SCI is research which 226 00:11:55,360 --> 00:12:00,760 now exists on the I we 227 00:12:00,760 --> 00:12:03,800 I other disciplines cardiology 228 00:12:03,800 --> 00:12:07,839 oncology rheumatology 229 00:12:13,040 --> 00:12:15,360 gastroenterology Cornélia suffers from 230 00:12:15,360 --> 00:12:17,920 fibromyalgia a disease that causes 231 00:12:17,920 --> 00:12:21,800 terrible muscle pain and 232 00:12:23,959 --> 00:12:26,040 joints classical medicine does not 233 00:12:26,040 --> 00:12:31,160 has no great hope treatment 234 00:12:32,639 --> 00:12:34,959 sick the first time I came 235 00:12:34,959 --> 00:12:37,160 in the hospital I could no longer do 236 00:12:37,160 --> 00:12:39,839 bike I walked very slowly I 237 00:12:39,839 --> 00:12:41,839 could barely move my knee I had 238 00:12:41,839 --> 00:12:44,279 back pain was all the time 239 00:12:44,279 --> 00:12:46,560 unbearable I consulted doctors 240 00:12:46,560 --> 00:12:48,399 for years I took a lot of 241 00:12:48,399 --> 00:12:50,160 different medications but pain 242 00:12:50,160 --> 00:12:52,800 was always 243 00:12:54,760 --> 00:12:58,000 there the doctors observed that the young 244 00:12:58,000 --> 00:13:00,000 acts all the better is associated with 245 00:13:00,000 --> 00:13:03,120 other massage therapies 246 00:13:03,120 --> 00:13:08,880 suction cup cold therapy at 110 247 00:13:09,480 --> 00:13:13,000 deg and exercise 248 00:13:13,000 --> 00:13:16,720 physical the goal to eliminate waste from 249 00:13:16,720 --> 00:13:19,600 the body stimulates autophagy 250 00:13:19,600 --> 00:13:22,040 reduce 251 00:13:23,519 --> 00:13:25,639 inflammation I came here for 252 00:13:25,639 --> 00:13:27,360 see what I could bring to the 253 00:13:27,360 --> 00:13:29,240 therapeutic plan 254 00:13:29,240 --> 00:13:31,040 impressed me the most is seeing 255 00:13:31,040 --> 00:13:32,360 patients arrive with 256 00:13:32,360 --> 00:13:34,959 very swollen joints and there 257 00:13:34,959 --> 00:13:37,959 after 24 hours 48 hours or later 258 00:13:37,959 --> 00:13:40,440 nothing the joint had regained its 259 00:13:40,440 --> 00:13:42,959 normal appearance had become thin again and 260 00:13:42,959 --> 00:13:45,120 functional people no longer suffered 261 00:13:45,120 --> 00:13:47,680 or very little and it totally fascinated me 262 00:13:47,680 --> 00:13:49,279 because I had never seen anything 263 00:13:49,279 --> 00:13:51,040 the same and I had never heard of it 264 00:13:51,040 --> 00:13:52,720 talk during my studies about 265 00:13:52,720 --> 00:13:56,360 medicine I said to myself it's possible 266 00:13:56,360 --> 00:14:00,639 why has no one ever told me about it 267 00:14:00,959 --> 00:14:03,160 from metabolic syndrome to the microbiota in 268 00:14:03,160 --> 00:14:05,279 going through inflammatory diseases 269 00:14:05,279 --> 00:14:08,040 Andreas Michelson's team multiplies 270 00:14:08,040 --> 00:14:11,399 studies on the effects of 271 00:14:12,360 --> 00:14:14,320 fasting fasting has effects 272 00:14:14,320 --> 00:14:17,040 most important sibl therapeutics 273 00:14:17,040 --> 00:14:19,480 are the antirheumatic effect and 274 00:14:19,480 --> 00:14:22,120 anti-inflammatory in case of rheumatism 275 00:14:22,120 --> 00:14:25,120 osteoarthritis pain it is effective 276 00:14:25,120 --> 00:14:27,199 against type 2 diabetes and can 277 00:14:27,199 --> 00:14:30,240 cure everything like can be cured of 278 00:14:30,240 --> 00:14:32,959 fact it is preventive in diseases 279 00:14:32,959 --> 00:14:34,480 cardiovascular these are the 280 00:14:34,480 --> 00:14:36,440 main indications here in our 281 00:14:36,440 --> 00:14:38,160 medical service 282 00:14:38,160 --> 00:14:40,440 internal and here is the list of 283 00:14:40,440 --> 00:14:42,560 established contraindications for young people 284 00:14:42,560 --> 00:14:45,959 by German doctors hidden anorexia 285 00:14:45,959 --> 00:14:47,959 and eating disorder 286 00:14:47,959 --> 00:14:50,240 hyperthyroidism liver failure 287 00:14:50,240 --> 00:14:56,079 renal type 1 diabetes pregnancy 288 00:14:57,420 --> 00:15:00,570 [Music] 289 00:15:03,800 --> 00:15:07,240 Stéphane begins his 3rd day of fasting 290 00:15:07,240 --> 00:15:09,480 yet walks 2 hours a day 291 00:15:09,480 --> 00:15:13,560 several kilometers without 292 00:15:15,260 --> 00:15:16,720 [Music] 293 00:15:16,720 --> 00:15:19,199 how did his body weaken 294 00:15:19,199 --> 00:15:21,399 adapted to the deprivation of 295 00:15:21,399 --> 00:15:23,920 food triggering another 296 00:15:23,920 --> 00:15:26,560 mechanism inherited from evolution 297 00:15:26,560 --> 00:15:30,240 metabolic switch 298 00:15:31,600 --> 00:15:33,839 the body's main fuel 299 00:15:33,839 --> 00:15:37,399 it's glucose but this one stored 300 00:15:37,399 --> 00:15:40,079 in the form of glycogen is depleted 301 00:15:40,079 --> 00:15:43,720 after about 24 hours of fasting the body 302 00:15:43,720 --> 00:15:46,360 will then draw on the fats and 303 00:15:46,360 --> 00:15:48,480 it is the liver which will transform the 304 00:15:48,480 --> 00:15:50,759 fats into a new fuel 305 00:15:50,759 --> 00:15:53,720 ketones to fuel the brain and 306 00:15:53,720 --> 00:15:57,319 creates energy for 307 00:15:57,920 --> 00:16:00,920 muscles 308 00:16:06,399 --> 00:16:10,240 is at 13 309 00:16:26,199 --> 00:16:27,920 day 310 00:16:27,920 --> 00:16:31,880 now ketone ketones 311 00:16:31,880 --> 00:16:34,079 alternative fuel manufactured by the 312 00:16:34,079 --> 00:16:36,319 bodies have long had bad 313 00:16:36,319 --> 00:16:39,660 reputation but things have 314 00:16:39,660 --> 00:16:42,079 [Music] 315 00:16:42,079 --> 00:16:45,680 changed and if the ceons were not 316 00:16:45,680 --> 00:16:47,759 only an alternative fuel 317 00:16:47,759 --> 00:16:50,160 but a super fuel which would allow 318 00:16:50,160 --> 00:16:53,319 to work faster harder more 319 00:16:53,319 --> 00:16:56,319 long time 320 00:17:04,240 --> 00:17:07,079 Formula 1 enthusiast Éric Verdin on 321 00:17:07,079 --> 00:17:09,240 is 322 00:17:09,720 --> 00:17:12,280 convinced I like to compare in fact 323 00:17:12,280 --> 00:17:13,559 fuels than cars 324 00:17:13,559 --> 00:17:15,240 use with the fuels that our 325 00:17:15,240 --> 00:17:17,520 body uses so we imagine the ketones 326 00:17:17,520 --> 00:17:19,000 it would be the equivalent of the fuel that 327 00:17:19,000 --> 00:17:21,079 this car uses and the worst this 328 00:17:21,079 --> 00:17:23,000 would be carbohydrates 329 00:17:23,000 --> 00:17:25,720 carbohydrates that can be compared to 330 00:17:25,720 --> 00:17:28,039 diesel therefore each of these fuels 331 00:17:28,039 --> 00:17:30,090 burns more or less 332 00:17:30,090 --> 00:17:32,919 [Music] 333 00:17:32,919 --> 00:17:35,760 pure strategizing for living 334 00:17:35,760 --> 00:17:38,039 long in good health is the 335 00:17:38,039 --> 00:17:40,640 mission of the Buck Institute renowned for 336 00:17:40,640 --> 00:17:42,840 his research on the 337 00:17:42,840 --> 00:17:46,240 longevity Eric Verdin the director 338 00:17:46,240 --> 00:17:49,000 studies the link between nutrition and immunity 339 00:17:49,000 --> 00:17:50,720 and 340 00:17:50,720 --> 00:17:52,880 inflammation following a series 341 00:17:52,880 --> 00:17:55,159 experiment on cells first 342 00:17:55,159 --> 00:17:57,600 then on mice he discovered 343 00:17:57,600 --> 00:18:01,520 amazing new properties in 344 00:18:07,159 --> 00:18:09,679 keton the researchers compared two 345 00:18:09,679 --> 00:18:12,880 groups of mice one eats normally 346 00:18:12,880 --> 00:18:14,760 the other is in 347 00:18:14,760 --> 00:18:17,520 ketosis the mice are then subjected to 348 00:18:17,520 --> 00:18:19,880 memory exploration tests 349 00:18:19,880 --> 00:18:22,159 visual and recognition of a 350 00:18:22,159 --> 00:18:24,240 new 351 00:18:24,240 --> 00:18:27,200 object and mice placed in cose 352 00:18:27,200 --> 00:18:29,280 regularly throughout the 353 00:18:29,280 --> 00:18:31,200 perform better than those who have 354 00:18:31,200 --> 00:18:33,080 eaten 355 00:18:33,080 --> 00:18:35,720 normally their memory even improves 356 00:18:35,720 --> 00:18:37,919 in 357 00:18:38,120 --> 00:18:40,360 aging the classic vision of 358 00:18:40,360 --> 00:18:42,240 ketone is a fuel so it is a 359 00:18:42,240 --> 00:18:44,120 form of energy that the cell uses 360 00:18:44,120 --> 00:18:46,480 during the youth what we were able to show 361 00:18:46,480 --> 00:18:48,400 is that these are molecules which 362 00:18:48,400 --> 00:18:51,600 therefore signal that they have the capacity to 363 00:18:51,600 --> 00:18:53,280 change the way a cell 364 00:18:53,280 --> 00:18:56,480 works and in particular to induce a 365 00:18:56,480 --> 00:19:00,320 protection against oxidative stress 366 00:19:00,320 --> 00:19:02,360 oxidative stress is a bit like 367 00:19:02,360 --> 00:19:04,600 the rust that infiltrates the defenses of 368 00:19:04,600 --> 00:19:07,559 the cell and accelerates its 369 00:19:07,559 --> 00:19:10,159 aging the éc Verdin team has 370 00:19:10,159 --> 00:19:12,080 shown that ketones activate 371 00:19:12,080 --> 00:19:16,080 genes that protect against this stress 372 00:19:16,080 --> 00:19:18,799 oxidative so that that allowed 373 00:19:18,799 --> 00:19:21,240 directly to make a link between this 374 00:19:21,240 --> 00:19:23,720 what we knew about ketones and in fact 375 00:19:23,720 --> 00:19:25,640 the potential they had to 376 00:19:25,640 --> 00:19:28,120 to increase life expectancy and 377 00:19:28,120 --> 00:19:30,480 protect against 378 00:19:30,480 --> 00:19:34,000 patients, ketones would therefore slow down 379 00:19:34,000 --> 00:19:37,159 aging Éric Verdin sought 380 00:19:37,159 --> 00:19:39,919 the formula to synthesize them and 381 00:19:39,919 --> 00:19:42,240 found 382 00:19:44,360 --> 00:19:47,720 one with the help of a chemist he 383 00:19:47,720 --> 00:19:49,840 successfully made ketones 384 00:19:49,840 --> 00:19:52,120 identical to those normally produced 385 00:19:52,120 --> 00:19:56,520 by the body during a fast 386 00:19:59,600 --> 00:20:02,080 shake 387 00:20:04,720 --> 00:20:09,320 first it tastes like a like a 388 00:20:10,240 --> 00:20:12,960 yogurt les ctones made in 389 00:20:12,960 --> 00:20:15,280 laboratory will they one day be prescribed 390 00:20:15,280 --> 00:20:16,919 to slow down aging and 391 00:20:16,919 --> 00:20:19,840 halting cognitive decline is 392 00:20:19,840 --> 00:20:24,600 the hypothesis explored at the Buck Institute 393 00:20:33,679 --> 00:20:35,080 they have just launched a study 394 00:20:35,080 --> 00:20:38,640 preliminary with 30 395 00:20:44,159 --> 00:20:48,240 volunteer OK 396 00:20:59,320 --> 00:21:01,640 6th day of fasting for 397 00:21:01,640 --> 00:21:04,720 Stéphane the rate of stupidity he makes 398 00:21:04,720 --> 00:21:07,690 naturally continues to rise 399 00:21:07,690 --> 00:21:31,039 [Music] 400 00:21:31,039 --> 00:21:32,200 I think what is really 401 00:21:32,200 --> 00:21:34,039 powerful in the young and it is 402 00:21:34,039 --> 00:21:35,559 why it acts on so many systems 403 00:21:35,559 --> 00:21:37,559 different is that it increases tenfold the 404 00:21:37,559 --> 00:21:40,480 body's ability to 405 00:21:40,480 --> 00:21:42,799 self-repair fasting sends a signal 406 00:21:42,799 --> 00:21:45,400 to the human body or to the mouse it is 407 00:21:45,400 --> 00:21:47,600 time to start a regeneration at 408 00:21:47,600 --> 00:21:50,360 several levels let's try to fix it 409 00:21:50,360 --> 00:21:52,420 maximum possible things 410 00:21:52,420 --> 00:22:00,490 [Music] 411 00:22:10,840 --> 00:22:13,159 Valter Longo explores the effects of 412 00:22:13,159 --> 00:22:15,000 food restriction for almost 413 00:22:15,000 --> 00:22:18,960 30 years old born in Italy he immigrated at 16 414 00:22:18,960 --> 00:22:20,600 years in the United States to become a 415 00:22:20,600 --> 00:22:22,670 rockstar 416 00:22:22,670 --> 00:22:25,789 [Music] 417 00:22:27,930 --> 00:22:34,320 [Music] 418 00:22:34,320 --> 00:22:36,799 but today he put his guitar away 419 00:22:36,799 --> 00:22:39,080 and became a search star 420 00:22:39,080 --> 00:22:40,679 on the 421 00:22:40,679 --> 00:22:43,960 longevity its purpose repelling diseases 422 00:22:43,960 --> 00:22:46,039 of 423 00:22:46,440 --> 00:22:49,799 old age we filmed it in 2011 it 424 00:22:49,799 --> 00:22:51,640 had just carried out an experiment which 425 00:22:51,640 --> 00:22:54,200 had shaken the community 426 00:22:54,200 --> 00:22:56,600 scientist mice with 427 00:22:56,600 --> 00:22:58,520 cancer who had fasted before 428 00:22:58,520 --> 00:23:00,799 high dose chemotherapy was 429 00:23:00,799 --> 00:23:03,200 protected from toxic side effects 430 00:23:03,200 --> 00:23:04,039 of 431 00:23:04,039 --> 00:23:06,720 treatment of the tests had then been 432 00:23:06,720 --> 00:23:08,360 launched on patients in several 433 00:23:08,360 --> 00:23:12,559 hospitals with fasting at 434 00:23:15,240 --> 00:23:17,559 water so we started with a 435 00:23:17,559 --> 00:23:19,360 water fasting in mice and 436 00:23:19,360 --> 00:23:22,520 humans and patients surprisingly 437 00:23:22,520 --> 00:23:25,440 water fasting was rejected, it was 438 00:23:25,440 --> 00:23:27,960 felt cheated he told us why 439 00:23:27,960 --> 00:23:30,799 you give me water I have cancer 440 00:23:30,799 --> 00:23:32,640 everyone was very worried 441 00:23:32,640 --> 00:23:34,640 families patients the oncologist 442 00:23:34,640 --> 00:23:37,840 general everyone was 443 00:23:37,840 --> 00:23:40,720 worried and that's how we got 444 00:23:40,720 --> 00:23:43,120 started so we had to find a 445 00:23:43,120 --> 00:23:45,799 alternative for young people to 446 00:23:45,799 --> 00:23:48,400 water after years of research 447 00:23:48,400 --> 00:23:50,600 laboratory with funding from 448 00:23:50,600 --> 00:23:53,000 the National Cancer Institute 449 00:23:53,000 --> 00:23:55,880 Americanter Longo created the fasting 450 00:23:55,880 --> 00:23:57,440 mimicking 451 00:23:57,440 --> 00:24:01,640 diet diet imitating 452 00:24:01,640 --> 00:24:04,520 very low calorie fast this 453 00:24:04,520 --> 00:24:06,679 diet causes in the body certain 454 00:24:06,679 --> 00:24:08,640 biological changes observed during 455 00:24:08,640 --> 00:24:12,400 a fast and in particular a passage 456 00:24:12,400 --> 00:24:16,760 encetosis 600 calories the first day 457 00:24:16,760 --> 00:24:19,110 300 for 4 days 458 00:24:19,110 --> 00:24:21,640 [Music] 459 00:24:21,640 --> 00:24:23,760 following but while first 460 00:24:23,760 --> 00:24:25,440 clinical trials with this diet 461 00:24:25,440 --> 00:24:27,159 shows a reduction in the effects 462 00:24:27,159 --> 00:24:30,360 secondary in AP 463 00:24:30,960 --> 00:24:34,279 dear F un nel 464 00:24:37,919 --> 00:24:40,919 objective while initially we were looking for 465 00:24:40,919 --> 00:24:43,760 to protect the patient today we 466 00:24:43,760 --> 00:24:47,320 aims for his recovery it's a huge 467 00:24:47,320 --> 00:24:49,200 difference and it's a moment 468 00:24:49,200 --> 00:24:51,360 exciting because we are talking now 469 00:24:51,360 --> 00:24:53,720 adaptation mechanism to deprivation 470 00:24:53,720 --> 00:24:58,520 of food Dei became agitated 471 00:24:58,520 --> 00:25:00,720 imitating fasting corners cancer into 472 00:25:00,720 --> 00:25:01,559 a 473 00:25:01,559 --> 00:25:04,200 corner the cancer then activates two or 474 00:25:04,200 --> 00:25:06,760 three survival mechanisms and we 475 00:25:06,760 --> 00:25:09,679 uses medications to block these 476 00:25:09,679 --> 00:25:11,919 mechanisms and it works very well 477 00:25:11,919 --> 00:25:14,279 among the 478 00:25:14,559 --> 00:25:17,520 mouse in constant search of energy 479 00:25:17,520 --> 00:25:20,760 to proliferate but starved by fasting 480 00:25:20,760 --> 00:25:23,000 Activ cancer cells 481 00:25:23,000 --> 00:25:25,000 desperately certain mechanisms of 482 00:25:25,000 --> 00:25:27,480 survival to capture nutrients again 483 00:25:27,480 --> 00:25:29,480 available 484 00:25:29,480 --> 00:25:31,120 these molecules then become 485 00:25:31,120 --> 00:25:34,480 targets for treatments 486 00:25:45,000 --> 00:25:47,919 antiancer pass from mice to humans 487 00:25:47,919 --> 00:25:51,279 this is always the major issue in 488 00:25:51,279 --> 00:25:53,520 biology department head in one of the 489 00:25:53,520 --> 00:25:55,880 largest Italian cancer centers 490 00:25:55,880 --> 00:25:57,760 Professor Vernier is one of the 491 00:25:57,760 --> 00:25:59,559 numerous researchers who collaborate with 492 00:25:59,559 --> 00:26:01,960 Valter 493 00:26:02,159 --> 00:26:05,200 Longo the oncologist proposed to a 494 00:26:05,200 --> 00:26:08,039 hundred patients including 75% at one 495 00:26:08,039 --> 00:26:11,159 advanced stage with metastasis to follow 496 00:26:11,159 --> 00:26:13,039 several diet cures imitating the 497 00:26:13,039 --> 00:26:15,039 fasting in combination with 498 00:26:15,039 --> 00:26:18,279 anti-ancer treatments 499 00:26:19,880 --> 00:26:22,320 classics we demonstrated with this first 500 00:26:22,320 --> 00:26:24,679 Clinical ESS than this 5-day protocol 501 00:26:24,679 --> 00:26:26,960 diet imitating fasting is without 502 00:26:26,960 --> 00:26:28,840 danger is feasible in patients 503 00:26:28,840 --> 00:26:30,039 wait for 504 00:26:30,039 --> 00:26:32,399 cancer the vast majority of patients 505 00:26:32,399 --> 00:26:33,919 do not lose weight over the 506 00:26:33,919 --> 00:26:35,440 cycles of this 507 00:26:35,440 --> 00:26:37,880 diet is very important because the 508 00:26:37,880 --> 00:26:40,039 cachexia malnutrition and loss 509 00:26:40,039 --> 00:26:41,720 muscle can be problems 510 00:26:41,720 --> 00:26:44,080 major in some patients this is not 511 00:26:44,080 --> 00:26:46,000 therefore not the case provided that the 512 00:26:46,000 --> 00:26:47,960 patients are seriously followed by 513 00:26:47,960 --> 00:26:50,840 doctors and 514 00:26:50,840 --> 00:26:52,880 nutritionists but the young among 515 00:26:52,880 --> 00:26:55,120 Does it cause the same effects in patients? 516 00:26:55,120 --> 00:26:59,240 biological than in mice 517 00:27:00,159 --> 00:27:01,679 we observed in the blood of these 518 00:27:01,679 --> 00:27:03,840 patients a significant reduction and 519 00:27:03,840 --> 00:27:06,720 constant insulin glucose levels 520 00:27:06,720 --> 00:27:09,440 and growth factor and at the same time 521 00:27:09,440 --> 00:27:11,600 time an increase in cunts in the 522 00:27:11,600 --> 00:27:14,000 plasma and urine are effects 523 00:27:14,000 --> 00:27:16,120 metabolic corresponds to the change 524 00:27:16,120 --> 00:27:18,240 metabolism responsible for the effects 525 00:27:18,240 --> 00:27:20,420 anticancer of I at home 526 00:27:20,420 --> 00:27:23,039 [Music] 527 00:27:23,039 --> 00:27:25,600 mouse researchers observe that the 528 00:27:25,600 --> 00:27:28,480 young also acts another level all 529 00:27:28,480 --> 00:27:30,799 also 530 00:27:32,799 --> 00:27:35,640 important the other discovery concerned 531 00:27:35,640 --> 00:27:38,399 the attack of cancer by the system 532 00:27:38,399 --> 00:27:40,799 immune system they therefore examined 533 00:27:40,799 --> 00:27:42,919 infiltration of immune cells 534 00:27:42,919 --> 00:27:44,600 in the 535 00:27:44,600 --> 00:27:48,320 tumor T lymphocytes cells 536 00:27:48,320 --> 00:27:50,120 essential killers in the answer 537 00:27:50,120 --> 00:27:52,480 immune to cancer were 538 00:27:52,480 --> 00:27:54,159 increased in the blood of patients who 539 00:27:54,159 --> 00:27:56,360 had followed a fast as among the 540 00:27:56,360 --> 00:27:58,679 mouse 541 00:27:58,679 --> 00:28:01,039 on the left a tumor tissue 542 00:28:01,039 --> 00:28:04,440 cancerous and here is after a fast of 5 543 00:28:04,440 --> 00:28:07,440 days this same cancerous tissue invaded by 544 00:28:07,440 --> 00:28:11,320 immune cells in 545 00:28:14,520 --> 00:28:21,200 [Music] 546 00:28:21,200 --> 00:28:24,600 brown for C patients the result was 547 00:28:24,600 --> 00:28:26,960 exceptional enough for the 548 00:28:26,960 --> 00:28:31,559 researchers publish a specification on their 549 00:28:32,280 --> 00:28:33,720 [Music] 550 00:28:33,720 --> 00:28:36,159 cases in some patients with 551 00:28:36,159 --> 00:28:38,760 very aggressive and deadly cancer like a 552 00:28:38,760 --> 00:28:41,519 advanced pancreatic adenocarcinoma 553 00:28:41,519 --> 00:28:44,159 advanced small cell lung cancer 554 00:28:44,159 --> 00:28:46,720 or triple A negative breast cancer 555 00:28:46,720 --> 00:28:49,240 advanced we observed remissions 556 00:28:49,240 --> 00:28:52,760 complete and durable and it is rare and 557 00:28:52,760 --> 00:28:55,399 even very very rare to observe Tell 558 00:28:55,399 --> 00:28:58,320 complete and hard remission 559 00:28:58,320 --> 00:28:59,519 of these patients could be 560 00:28:59,519 --> 00:29:02,120 definitely 561 00:29:02,120 --> 00:29:04,799 heal as extraordinary as you 562 00:29:04,799 --> 00:29:07,120 results of this study they must 563 00:29:07,120 --> 00:29:09,240 present be confirmed by wide 564 00:29:09,240 --> 00:29:11,600 tests 565 00:29:13,159 --> 00:29:15,559 clinics there are probably more than 20 566 00:29:15,559 --> 00:29:17,760 ongoing clinical trials on cancer 567 00:29:17,760 --> 00:29:19,720 with fasting or diet imitating the 568 00:29:19,720 --> 00:29:21,840 fasting involving hundreds of 569 00:29:21,840 --> 00:29:25,159 Atte patients of different types of 570 00:29:25,159 --> 00:29:27,039 cancer so I encourage them 571 00:29:27,039 --> 00:29:30,159 comm oncologists to read the studies and 572 00:29:30,159 --> 00:29:31,600 after reading all the literature 573 00:29:31,600 --> 00:29:34,720 scientific it is up to them to decide 574 00:29:34,720 --> 00:29:37,000 will be able to say yes it is worth it in 575 00:29:37,000 --> 00:29:38,919 this particular case of proposing a diet 576 00:29:38,919 --> 00:29:41,200 imitating fasting or not it's still 577 00:29:41,200 --> 00:29:43,399 too much 578 00:29:48,159 --> 00:29:52,120 early 10th day of fasting for Stéphane more 579 00:29:52,120 --> 00:29:55,559 only 4 days without food and until then 580 00:29:55,559 --> 00:29:58,960 everything is fine 581 00:30:04,920 --> 00:30:23,440 [Music] 582 00:30:23,440 --> 00:30:25,880 Stéphane lost a few kilos but 583 00:30:25,880 --> 00:30:28,450 did he lose muscle 584 00:30:28,450 --> 00:30:30,200 [Music] 585 00:30:30,200 --> 00:30:33,440 the last reproach really which 586 00:30:33,440 --> 00:30:35,720 repeats generations of journalists in 587 00:30:35,720 --> 00:30:38,600 generation of doctors is the 588 00:30:38,600 --> 00:30:40,519 so-called muscle wasting which 589 00:30:40,519 --> 00:30:42,120 contradicts all our observation 590 00:30:42,120 --> 00:30:43,480 clinic us when we see a patient 591 00:30:43,480 --> 00:30:45,919 who arrives and we see him again two or three 592 00:30:45,919 --> 00:30:48,159 weeks later at the beginning it can even 593 00:30:48,159 --> 00:30:50,480 not climb the hill to the clinic without 594 00:30:50,480 --> 00:30:52,320 stop three times at the end of the stay 595 00:30:52,320 --> 00:30:55,080 he stops the more he rides it one by one 596 00:30:55,080 --> 00:30:57,039 not light so we could see that the 597 00:30:57,039 --> 00:30:58,840 muscle performance improves 598 00:30:58,840 --> 00:31:01,240 cardiac performance too but it 599 00:31:01,240 --> 00:31:03,240 had to document this and in a way 600 00:31:03,240 --> 00:31:04,770 very very 601 00:31:04,770 --> 00:31:06,279 [Music] 602 00:31:06,279 --> 00:31:08,760 convincing the clinic launches the study 603 00:31:08,760 --> 00:31:12,559 Genesis with researchers 604 00:31:13,320 --> 00:31:16,200 French Professor Pierre Croisille 605 00:31:16,200 --> 00:31:19,039 and physicist Magalie Vialon have 606 00:31:19,039 --> 00:31:22,120 measured by MRI the effects of fasting 607 00:31:22,120 --> 00:31:25,840 12 days a fast of such duration 608 00:31:25,840 --> 00:31:28,000 does it have deleterious effects on 609 00:31:28,000 --> 00:31:31,519 organs and in particular on the 610 00:31:31,519 --> 00:31:34,840 muscles when you fast you lose weight 611 00:31:34,840 --> 00:31:37,880 that's certain in the Genesis 612 00:31:37,880 --> 00:31:40,880 people lost roughly 6 kg in 613 00:31:40,880 --> 00:31:43,120 average the real question is about these 614 00:31:43,120 --> 00:31:45,159 6 kg what is water 615 00:31:45,159 --> 00:31:46,360 what is fat 616 00:31:46,360 --> 00:31:48,480 what is the 617 00:31:48,480 --> 00:31:51,639 muscle this study is a first 618 00:31:51,639 --> 00:31:52,480 is 619 00:31:52,480 --> 00:31:55,080 fundamental it could either sweep away 620 00:31:55,080 --> 00:31:57,320 the fears of critics of fasting 621 00:31:57,320 --> 00:32:01,600 is reinforced in the event of melting 622 00:32:01,600 --> 00:32:04,760 muscular 32 Young people of all ages have 623 00:32:04,760 --> 00:32:07,519 had MRI scans before their treatment at the end 624 00:32:07,519 --> 00:32:12,120 12 days then 1 and 4 months 625 00:32:12,120 --> 00:32:15,960 after nearly 70,000 images were 626 00:32:15,960 --> 00:32:18,880 carried out for each 627 00:32:22,919 --> 00:32:25,600 young person the good surprise is that the 628 00:32:25,600 --> 00:32:27,360 images that we have they demonstrate a 629 00:32:27,360 --> 00:32:28,519 preserves 630 00:32:28,519 --> 00:32:30,360 of the integrity of the muscle so there is there 631 00:32:30,360 --> 00:32:32,399 no change in muscle 632 00:32:32,399 --> 00:32:33,760 which allow us to say that there is a 633 00:32:33,760 --> 00:32:35,919 negative impact of fasting we have a 634 00:32:35,919 --> 00:32:37,480 preservation of its structure we have a 635 00:32:37,480 --> 00:32:38,919 preservation of its properties 636 00:32:38,919 --> 00:32:40,720 magnetic so we can say with 637 00:32:40,720 --> 00:32:43,360 certainty that it has no effect 638 00:32:43,360 --> 00:32:45,639 harmful of fasting on the on the 639 00:32:45,639 --> 00:32:47,200 muscle 640 00:32:47,200 --> 00:32:50,360 The structure of the muscle itself is therefore 641 00:32:50,360 --> 00:32:52,880 preserved but what about its 642 00:32:52,880 --> 00:32:58,600 ability to exert effort go 3 2 1 643 00:32:58,600 --> 00:33:00,840 Go go go push push push 644 00:33:00,840 --> 00:33:03,559 Push stop, this is the most incredible 645 00:33:03,559 --> 00:33:06,279 it was that people spent 12 days of 646 00:33:06,279 --> 00:33:09,440 young person was able to provide the same 647 00:33:09,440 --> 00:33:12,799 maximum effort as before same 648 00:33:12,799 --> 00:33:15,960 for the exercise test part and the 649 00:33:15,960 --> 00:33:18,600 oxidative functioning of the muscle 650 00:33:18,600 --> 00:33:21,559 remains as effective it was also 651 00:33:21,559 --> 00:33:23,639 well after you stop eating 652 00:33:23,639 --> 00:33:25,360 for 12 days while often we go 653 00:33:25,360 --> 00:33:27,399 tell you before going for a run 654 00:33:27,399 --> 00:33:28,880 you have to eat a little bit otherwise you 655 00:33:28,880 --> 00:33:30,440 going to have a 656 00:33:30,440 --> 00:33:32,360 hypoglycemia that's still enough 657 00:33:32,360 --> 00:33:34,919 surprising when 658 00:33:34,919 --> 00:33:38,600 even on the muscle side so no 659 00:33:38,600 --> 00:33:40,960 problem but what is happening 660 00:33:40,960 --> 00:33:42,470 level of others 661 00:33:42,470 --> 00:33:43,919 [Music] 662 00:33:43,919 --> 00:33:46,440 organs the analyzes show that the 663 00:33:46,440 --> 00:33:49,960 brain the heart the abdomen including the liver 664 00:33:49,960 --> 00:33:53,519 fits perfectly with the switch 665 00:33:53,519 --> 00:33:56,480 metabolic rate for visceral fat 666 00:33:56,480 --> 00:33:58,200 a major risk factor 667 00:33:58,200 --> 00:34:00,919 cardiovascular it was reduced 668 00:34:00,919 --> 00:34:05,200 she was still 4 months after the 669 00:34:05,679 --> 00:34:08,399 fast this type of scientific study which 670 00:34:08,399 --> 00:34:10,239 allows with images to demonstrate 671 00:34:10,239 --> 00:34:12,560 that there is no negative impact of fasting 672 00:34:12,560 --> 00:34:14,359 on our main organs whether 673 00:34:14,359 --> 00:34:15,639 the liver whether it is the heart or the 674 00:34:15,639 --> 00:34:17,760 brain whether it’s muscle it’s for me 675 00:34:17,760 --> 00:34:19,879 seems fundamental because it allows 676 00:34:19,879 --> 00:34:20,879 then 677 00:34:20,879 --> 00:34:23,639 to postpone the fast in a 678 00:34:23,639 --> 00:34:25,960 difficulty which is only mental 679 00:34:25,960 --> 00:34:28,079 there is no harm 680 00:34:28,079 --> 00:34:30,280 whoever there is, there's nothing 681 00:34:30,280 --> 00:34:32,440 become anxious at the physiological level by 682 00:34:32,440 --> 00:34:34,119 a young therapeutic person and that’s what we 683 00:34:34,119 --> 00:34:35,760 demonstrates with imagery at most 684 00:34:35,760 --> 00:34:38,639 deep within each of our 685 00:34:38,800 --> 00:34:42,280 organs in Berlin last day of fasting 686 00:34:42,280 --> 00:34:44,040 for 687 00:34:44,040 --> 00:34:47,440 Cornélia in her case her cure even 688 00:34:47,440 --> 00:34:51,520 allowed you to regain all your abilities 689 00:34:53,399 --> 00:34:56,239 muscles since I fasted I do 690 00:34:56,239 --> 00:34:58,640 cycling again I started again 691 00:34:58,640 --> 00:35:02,119 swim I walk I started again 692 00:35:02,119 --> 00:35:04,359 taste for life and it is a feeling of 693 00:35:04,359 --> 00:35:06,800 freedom I no longer feel cramped in 694 00:35:06,800 --> 00:35:08,920 this 695 00:35:09,359 --> 00:35:11,680 body but how to maintain 696 00:35:11,680 --> 00:35:13,839 improvements that occurred during treatment 697 00:35:13,839 --> 00:35:17,000 of fasting is the whole point of the return to 698 00:35:17,000 --> 00:35:19,119 the 699 00:35:19,720 --> 00:35:22,440 home we recommend fasting 700 00:35:22,440 --> 00:35:25,520 intermittent to almost all patients 701 00:35:25,520 --> 00:35:28,240 there are very few contraindications I 702 00:35:28,240 --> 00:35:29,920 intermittent we recommend 703 00:35:29,920 --> 00:35:32,200 systematically a daily fast of 14 704 00:35:32,200 --> 00:35:36,040 he after a therapeutic fast 705 00:35:37,920 --> 00:35:41,040 here prolong the effects of a long fast 706 00:35:41,040 --> 00:35:43,320 by a shorter fasting formula is 707 00:35:43,320 --> 00:35:45,599 a new idea it comes from 708 00:35:45,599 --> 00:35:47,680 astonishing research that launched a 709 00:35:47,680 --> 00:35:50,160 revolution 710 00:35:50,720 --> 00:35:53,040 food among the major players in 711 00:35:53,040 --> 00:35:59,290 this revolution Mar Matson etch panda 712 00:35:59,290 --> 00:36:05,119 [Music] 713 00:36:05,119 --> 00:36:07,960 they laid the scientific foundations of 714 00:36:07,960 --> 00:36:10,599 intermittent fasting, i.e. 715 00:36:10,599 --> 00:36:12,640 total abstention from food during 716 00:36:12,640 --> 00:36:18,240 12 to 14 or even 4 p.m. each 717 00:36:18,300 --> 00:36:22,019 [Music] 718 00:36:22,440 --> 00:36:24,960 day when we started this research 719 00:36:24,960 --> 00:36:27,880 in the 90s 720 00:36:27,880 --> 00:36:29,440 fundamental research will take 721 00:36:29,440 --> 00:36:31,640 such magnitude not only in the 722 00:36:31,640 --> 00:36:33,720 scientific or clinical field but 723 00:36:33,720 --> 00:36:35,640 throughout society where young people 724 00:36:35,640 --> 00:36:37,280 intermittent has now become 725 00:36:37,280 --> 00:36:39,780 something 726 00:36:39,780 --> 00:36:43,159 [Music] 727 00:36:51,480 --> 00:36:55,680 huge onelle that one I intermittent that 728 00:36:55,680 --> 00:36:59,520 stern what does it consist of 729 00:37:00,240 --> 00:37:02,160 in a few years the young 730 00:37:02,160 --> 00:37:04,160 intermittent has become a real 731 00:37:04,160 --> 00:37:05,560 phenomenon of 732 00:37:05,560 --> 00:37:07,960 company this adventure began at 733 00:37:07,960 --> 00:37:09,920 the National Institute on Aging 734 00:37:09,920 --> 00:37:12,800 in the United States with Marc Matson 735 00:37:12,800 --> 00:37:16,280 disease specialist 736 00:37:16,720 --> 00:37:18,839 neurodegenerative diseases the researcher wanted 737 00:37:18,839 --> 00:37:21,160 know if a young intermittent worker would have 738 00:37:21,160 --> 00:37:25,240 an influence on the functioning of the 739 00:37:25,240 --> 00:37:28,040 brain in this test to get out of 740 00:37:28,040 --> 00:37:30,480 water Alzheimer mice must 741 00:37:30,480 --> 00:37:32,599 find a submerged platform that we 742 00:37:32,599 --> 00:37:34,520 showed them 743 00:37:34,520 --> 00:37:37,000 previously the Alzheimer mouse which has 744 00:37:37,000 --> 00:37:42,839 eaten normally swim swim and swim 745 00:37:43,960 --> 00:37:46,240 still so she is not capable of 746 00:37:46,240 --> 00:37:48,079 get out of the water and climb on the 747 00:37:48,079 --> 00:37:50,160 platform because she doesn't remember 748 00:37:50,160 --> 00:37:53,119 not the location of the 749 00:37:54,200 --> 00:37:56,760 Madson platform redone then 750 00:37:56,760 --> 00:37:57,960 the experience 751 00:37:57,960 --> 00:37:59,839 but this time the Alzheimer mouse 752 00:37:59,839 --> 00:38:01,880 has been practicing intermittent fasting since 753 00:38:01,880 --> 00:38:04,040 several 754 00:38:04,040 --> 00:38:07,160 month the mouseheimer which followed a i 755 00:38:07,160 --> 00:38:09,119 intermittent has retained his faculties 756 00:38:09,119 --> 00:38:11,440 learning and memory all of 757 00:38:11,440 --> 00:38:14,760 following the difference platform 758 00:38:14,760 --> 00:38:18,640 yes it's a discovery 759 00:38:19,670 --> 00:38:24,200 [Music] 760 00:38:24,200 --> 00:38:28,200 extraordinary estcryp 761 00:38:28,319 --> 00:38:32,599 ind by intermittent fasting on the 762 00:38:33,800 --> 00:38:36,960 brain when you fast the activity of 763 00:38:36,960 --> 00:38:39,119 certain neural circuits increase 764 00:38:39,119 --> 00:38:41,400 in many areas of your 765 00:38:41,400 --> 00:38:44,400 brain it creates stress in the 766 00:38:44,400 --> 00:38:47,640 neurons and it improves their 767 00:38:47,640 --> 00:38:50,160 functioning of young intermittent 768 00:38:50,160 --> 00:38:52,200 induces in mice the production of 769 00:38:52,200 --> 00:38:54,599 Activ molecules named factor 770 00:38:54,599 --> 00:38:57,599 neurotropic 771 00:38:57,760 --> 00:38:59,760 V then stimulate the creation of new 772 00:38:59,760 --> 00:39:02,160 neurons in the hippocampus an area of the 773 00:39:02,160 --> 00:39:04,040 brain precisely involved in 774 00:39:04,040 --> 00:39:07,280 mson learning and memory 775 00:39:07,280 --> 00:39:09,400 recalls that in the human animal kingdom 776 00:39:09,400 --> 00:39:12,079 understood a hungry brain has an interest in 777 00:39:12,079 --> 00:39:15,960 have effective neurons for 778 00:39:15,960 --> 00:39:18,079 survive and it is 779 00:39:18,079 --> 00:39:21,040 logical they are more active because 780 00:39:21,040 --> 00:39:22,800 your brain must be able to 781 00:39:22,800 --> 00:39:25,319 spot or find food well 782 00:39:25,319 --> 00:39:26,680 sure today I just have to go to 783 00:39:26,680 --> 00:39:28,520 refrigerator 784 00:39:28,520 --> 00:39:30,160 but our hunter-gatherer ancestors 785 00:39:30,160 --> 00:39:32,400 had to visualize kilometers and 786 00:39:32,400 --> 00:39:35,200 kilometers of 787 00:39:36,160 --> 00:39:38,280 territory what is there what 788 00:39:38,280 --> 00:39:39,920 time of year at what time 789 00:39:39,920 --> 00:39:42,040 day what are the habits of the 790 00:39:42,040 --> 00:39:44,640 prey of 791 00:39:46,880 --> 00:39:49,200 the animal like an echo is this 792 00:39:49,200 --> 00:39:52,280 ancestral search for food mson 793 00:39:52,280 --> 00:39:54,520 also observes a positive effect of young 794 00:39:54,520 --> 00:39:56,079 intermittent throughout 795 00:39:56,079 --> 00:39:57,680 the organism 796 00:39:57,680 --> 00:40:00,800 [Music] 797 00:40:01,319 --> 00:40:04,000 why the last piece of the puzzle 798 00:40:04,000 --> 00:40:06,440 it's sachine panda who will bring it 799 00:40:06,440 --> 00:40:10,240 with his research on rhythms 800 00:40:10,920 --> 00:40:13,520 circadians our body is governed by 801 00:40:13,520 --> 00:40:16,599 24 hour clock cycles 802 00:40:16,599 --> 00:40:19,160 internal biological synchronized between 803 00:40:19,160 --> 00:40:22,359 them by the alternation of day and night 804 00:40:22,359 --> 00:40:25,319 night these clocks regulate many 805 00:40:25,319 --> 00:40:27,599 biological processes like sleep 806 00:40:27,599 --> 00:40:30,400 or digestion depending on 807 00:40:30,400 --> 00:40:33,040 hours the discovery of the mechanisms 808 00:40:33,040 --> 00:40:35,599 molecules controlling these aalu rhythms 809 00:40:35,599 --> 00:40:38,920 in 2017 a Nobel Prize in Medicine to TR 810 00:40:38,920 --> 00:40:41,319 others 811 00:40:42,040 --> 00:40:45,079 researchers it is incredible to realize 812 00:40:45,079 --> 00:40:47,640 that our body is programmed to 813 00:40:47,640 --> 00:40:50,000 achieve optimal performance 814 00:40:50,000 --> 00:40:53,000 each hour of the 815 00:40:54,400 --> 00:40:57,720 day our way of life can 816 00:40:57,720 --> 00:40:58,800 clocks 817 00:40:58,800 --> 00:41:03,680 internal a series of experiments will 818 00:41:04,280 --> 00:41:06,440 demonstrate two groups of mice will 819 00:41:06,440 --> 00:41:08,280 eat the same food rich in 820 00:41:08,280 --> 00:41:11,520 fat and sugar a group eats at 821 00:41:11,520 --> 00:41:14,839 any time 24 hours a day 822 00:41:14,839 --> 00:41:16,880 the other group is intermittent fasting 823 00:41:16,880 --> 00:41:19,440 and only eats 10 hours per 824 00:41:19,440 --> 00:41:22,680 day 4 months later the mice 825 00:41:22,680 --> 00:41:24,520 first group became obese 826 00:41:24,520 --> 00:41:26,680 diabetics with fatty liver and 827 00:41:26,680 --> 00:41:29,240 complications 828 00:41:32,520 --> 00:41:35,280 to our great surprise the second group 829 00:41:35,280 --> 00:41:37,520 of mice having consumed the same number 830 00:41:37,520 --> 00:41:39,960 calories from the same diet 831 00:41:39,960 --> 00:41:43,480 unbalanced and perfectly healthy 832 00:41:43,480 --> 00:41:44,960 they also had more endurance to 833 00:41:44,960 --> 00:41:47,079 the 834 00:41:47,480 --> 00:41:49,440 [Music] 835 00:41:49,440 --> 00:41:51,880 race at the time it didn't strike me 836 00:41:51,880 --> 00:41:53,760 at this point but I realize today 837 00:41:53,760 --> 00:41:55,839 that this is a major advance in 838 00:41:55,839 --> 00:41:58,839 last 150 years 839 00:41:58,839 --> 00:42:01,359 nutrition the conclusion of the study 840 00:42:01,359 --> 00:42:03,720 becomes a slogan better count the 841 00:42:03,720 --> 00:42:07,000 hours that calories are so much 842 00:42:07,000 --> 00:42:08,880 revolutionary that the community 843 00:42:08,880 --> 00:42:12,160 scientist reacts with 844 00:42:12,240 --> 00:42:16,599 skepticism sachine panda reverses then 845 00:42:16,599 --> 00:42:18,839 the experience this time is 846 00:42:18,839 --> 00:42:21,599 obese mice which will fast for 14 hours each 847 00:42:21,599 --> 00:42:24,440 day an eating rhythm that respects 848 00:42:24,440 --> 00:42:27,880 their internal biological clock 849 00:42:27,880 --> 00:42:30,559 and the mice lose weight 850 00:42:30,559 --> 00:42:32,960 health 851 00:42:33,800 --> 00:42:36,040 gets better that's where it's really been 852 00:42:36,040 --> 00:42:38,839 a revelation because it warns and it 853 00:42:38,839 --> 00:42:41,319 inverse it therefore means that the I 854 00:42:41,319 --> 00:42:42,920 intermittent could potentially 855 00:42:42,920 --> 00:42:45,440 prevent, control and treat 856 00:42:45,440 --> 00:42:48,559 metabolic diseases in 857 00:42:51,760 --> 00:42:54,559 humansyimentair to set our clock 858 00:42:54,559 --> 00:42:57,559 Inter 859 00:42:58,760 --> 00:43:02,040 expion in our world 860 00:43:07,400 --> 00:43:10,880 modern panda ve verify the hypothesis to 861 00:43:10,880 --> 00:43:14,599 how often to eat them 862 00:43:15,920 --> 00:43:18,760 could humans be like 863 00:43:18,760 --> 00:43:21,000 smile he got sick because they don't 864 00:43:21,000 --> 00:43:22,640 don't take a food break 865 00:43:22,640 --> 00:43:26,240 long enough 866 00:43:28,000 --> 00:43:30,240 researchers ask 150 residents 867 00:43:30,240 --> 00:43:32,400 from San Diego to photograph everything 868 00:43:32,400 --> 00:43:35,240 that they eat to note the schedule then 869 00:43:35,240 --> 00:43:37,839 to send the 870 00:43:39,760 --> 00:43:43,079 photos interviewed before the study 871 00:43:43,079 --> 00:43:44,760 participants all responded that it 872 00:43:44,760 --> 00:43:48,359 ate healthily and in a manner 873 00:43:48,359 --> 00:43:50,680 reasonable data analysis 874 00:43:50,680 --> 00:43:53,839 tells a completely different story 875 00:43:56,040 --> 00:43:57,680 history 876 00:43:57,680 --> 00:44:02,240 ps av Mang drunk over a period of 15 hours or 877 00:44:02,240 --> 00:44:06,040 no longer a shock it opened my eyes 878 00:44:06,040 --> 00:44:09,520 eyes therefore when we follow this mode of 879 00:44:09,520 --> 00:44:12,079 life we don't respect the clock 880 00:44:12,079 --> 00:44:14,359 internal Programm to tell us when 881 00:44:14,359 --> 00:44:16,520 we have to sleep every day when 882 00:44:16,520 --> 00:44:18,800 we have to eat 883 00:44:18,800 --> 00:44:22,160 fast then our metabolism our 884 00:44:22,160 --> 00:44:24,240 physiology and even our functions 885 00:44:24,240 --> 00:44:27,640 brains are disrupted 886 00:44:27,640 --> 00:44:29,160 and then the risk of contracting 887 00:44:29,160 --> 00:44:32,160 many diseases 888 00:44:32,160 --> 00:44:35,350 [Applause] 889 00:44:38,839 --> 00:44:42,119 increases the Institute's researchers 890 00:44:42,119 --> 00:44:43,920 are then interested in a population 891 00:44:43,920 --> 00:44:45,960 very special who works in 892 00:44:45,960 --> 00:44:48,440 schedule 893 00:44:56,040 --> 00:44:58,839 quirky person in excellent health 894 00:44:58,839 --> 00:45:00,440 unfortunately although it is 895 00:45:00,440 --> 00:45:02,319 From the start he very quickly develops 896 00:45:02,319 --> 00:45:03,400 diseases 897 00:45:03,400 --> 00:45:05,040 cardiometabolic it is even the 898 00:45:05,040 --> 00:45:06,559 leading cause of death among 899 00:45:06,559 --> 00:45:08,960 firefighters 900 00:45:09,160 --> 00:45:11,920 today this frightening observation has 901 00:45:11,920 --> 00:45:13,400 pushed researchers to conduct a 902 00:45:13,400 --> 00:45:15,359 experience of young intermittent worker with 903 00:45:15,359 --> 00:45:19,760 a Corte of 150 firefighters from San 904 00:45:21,640 --> 00:45:25,880 Diego shift schedule stressful work 905 00:45:25,880 --> 00:45:28,400 the firefighters are at 906 00:45:28,400 --> 00:45:30,680 snacking the researchers offer them 907 00:45:30,680 --> 00:45:34,319 a daily fast of 14 hours for 3 908 00:45:34,319 --> 00:45:37,599 month eliminate snacking in Paris 909 00:45:37,599 --> 00:45:40,839 was not so easy to 910 00:45:41,319 --> 00:45:43,880 hold we demonstrated that the young 911 00:45:43,880 --> 00:45:45,520 intermittent is a strategy 912 00:45:45,520 --> 00:45:47,240 feasible for workers to 913 00:45:47,240 --> 00:45:50,000 staggered schedules like the firefighters and 914 00:45:50,000 --> 00:45:51,640 in a group of firefighters suffering from 915 00:45:51,640 --> 00:45:54,480 latent cardiometabolic disease we have 916 00:45:54,480 --> 00:45:56,520 seen improvements including a 917 00:45:56,520 --> 00:45:59,440 lower the tension 918 00:45:59,440 --> 00:46:02,280 blood pressure in just 3 months 919 00:46:02,280 --> 00:46:05,079 PAM cardiologist who supervised the study 920 00:46:05,079 --> 00:46:08,040 observed 921 00:46:09,830 --> 00:46:11,280 [Music] 922 00:46:11,280 --> 00:46:13,319 improvements I think the game 923 00:46:13,319 --> 00:46:15,720 intermittent is really a strategy 924 00:46:15,720 --> 00:46:18,319 important for fighting disease 925 00:46:18,319 --> 00:46:19,880 cardiometabolic we have 926 00:46:19,880 --> 00:46:23,200 many medications but they are 927 00:46:23,200 --> 00:46:25,920 dear it is therefore essential to adopt 928 00:46:25,920 --> 00:46:27,720 good habits 929 00:46:27,720 --> 00:46:30,359 because it is a little strategy 930 00:46:30,359 --> 00:46:32,800 expensive it was also observed that the 931 00:46:32,800 --> 00:46:34,960 practice of intermittent youth persists 932 00:46:34,960 --> 00:46:37,160 over time because once 933 00:46:37,160 --> 00:46:39,640 people get used to it 934 00:46:39,640 --> 00:46:44,000 feel better which strengthens the 935 00:46:49,000 --> 00:46:51,640 practice and I saw results 936 00:46:51,640 --> 00:46:55,599 incredible in my patients 937 00:46:55,860 --> 00:46:59,079 [Music] 938 00:47:00,319 --> 00:47:01,559 many people in my 939 00:47:01,559 --> 00:47:03,599 laboratory have themselves adopted the game 940 00:47:03,599 --> 00:47:04,839 of 941 00:47:04,839 --> 00:47:06,880 intermittent I too started to 942 00:47:06,880 --> 00:47:09,440 eat over a very short period of time 943 00:47:09,440 --> 00:47:10,800 and I could immediately see the 944 00:47:10,800 --> 00:47:13,599 benefits for my 945 00:47:17,640 --> 00:47:20,240 health there is no consensus 946 00:47:20,240 --> 00:47:22,119 scientific on the ideal duration of 947 00:47:22,119 --> 00:47:24,800 young intermittent between 12 and 4 p.m. 948 00:47:24,800 --> 00:47:27,359 every day but researchers 949 00:47:27,359 --> 00:47:29,240 to only advise it from 950 00:47:29,240 --> 00:47:31,119 age 951 00:47:31,119 --> 00:47:33,680 adult to respond to doctors more 952 00:47:33,680 --> 00:47:35,480 more and more people are wondering about the 953 00:47:35,480 --> 00:47:37,680 runs a prestigious journal 954 00:47:37,680 --> 00:47:40,160 scientist asked Mark Matson to 955 00:47:40,160 --> 00:47:42,640 write a summary of its effects on 956 00:47:42,640 --> 00:47:44,920 the 957 00:47:45,319 --> 00:47:47,559 health I think there is today 958 00:47:47,559 --> 00:47:49,720 enough proof with the studies carried out 959 00:47:49,720 --> 00:47:51,599 in humans so that doctors 960 00:47:51,599 --> 00:47:53,040 are considering prescribing the young 961 00:47:53,040 --> 00:47:54,680 intermittent to people affected 962 00:47:54,680 --> 00:47:57,200 of obesity or diabetes or having one 963 00:47:57,200 --> 00:47:59,559 risk of developing these 964 00:47:59,559 --> 00:48:02,640 diseases and even diabetes 965 00:48:02,640 --> 00:48:05,040 many patients recover and do not have 966 00:48:05,040 --> 00:48:08,800 no more need for medication 967 00:48:11,340 --> 00:48:14,909 [Music] 968 00:48:17,800 --> 00:48:21,119 regulate 14th and last day of fasting 969 00:48:21,119 --> 00:48:25,760 for Stéphane during the first meal at 970 00:48:25,760 --> 00:48:28,440 sound good evening sir 971 00:48:28,440 --> 00:48:32,559 good evening congratulations 972 00:48:32,559 --> 00:48:37,280 thank you thank you and pourétit 973 00:48:37,960 --> 00:48:41,880 Sir it's a bit 974 00:48:42,720 --> 00:48:45,880 scared but I can't wait to find 975 00:48:45,880 --> 00:48:48,400 other food sensations and 976 00:48:48,400 --> 00:48:51,440 maybe chew 977 00:48:53,359 --> 00:48:58,079 above all it is well crunched 978 00:48:58,800 --> 00:49:05,590 [Music] 979 00:49:08,359 --> 00:49:10,839 it is also during the assessment 980 00:49:10,839 --> 00:49:14,000 medical how steatosis develops 981 00:49:14,000 --> 00:49:18,920 Stéphane's liver after 14 days of 982 00:49:19,040 --> 00:49:22,079 fasting when you have done the first exam 983 00:49:22,079 --> 00:49:24,520 the result was 984 00:49:24,520 --> 00:49:28,119 307 now it's 24 985 00:49:28,119 --> 00:49:29,920 so it's a big improvement after 986 00:49:29,920 --> 00:49:30,760 the 987 00:49:30,760 --> 00:49:33,839 fasting is almost a normal result 988 00:49:33,839 --> 00:49:36,359 it is therefore a 989 00:49:36,520 --> 00:49:39,720 success we no longer see fatty times 990 00:49:39,720 --> 00:49:41,319 now 991 00:49:41,319 --> 00:49:43,040 Chag 992 00:49:43,040 --> 00:49:46,280 non-alcoholic champagne no 993 00:49:46,280 --> 00:49:49,079 problem blood sugar is a lot 994 00:49:49,079 --> 00:49:50,599 improved that 995 00:49:50,599 --> 00:49:54,680 it's normalized it's excellent 996 00:49:54,680 --> 00:49:57,440 live very well they are 11 kg 997 00:49:57,440 --> 00:50:00,680 now excellent here it is and the turn of 998 00:50:00,680 --> 00:50:04,280 the size there was 112 now 999 00:50:04,280 --> 00:50:08,559 it's 104 okay 1000 00:50:08,559 --> 00:50:11,720 excellent after 14 days of fasting 1001 00:50:11,720 --> 00:50:14,520 Steatosis and Stéphane’s prediabetes 1002 00:50:14,520 --> 00:50:15,720 therefore have 1003 00:50:15,720 --> 00:50:20,720 [Music] 1004 00:50:20,720 --> 00:50:24,920 disappeared he lost 11 kg and 8 cm around 1005 00:50:24,920 --> 00:50:28,040 size 1006 00:50:29,130 --> 00:50:35,960 [Music] 1007 00:50:35,960 --> 00:50:39,359 to keep doctors' profits 1008 00:50:39,359 --> 00:50:41,760 insist on a food recovery 1009 00:50:41,760 --> 00:50:45,240 progressive over several days is 1010 00:50:45,240 --> 00:50:47,520 essential followed by the adoption of a 1011 00:50:47,520 --> 00:50:49,880 diet 1012 00:50:50,319 --> 00:50:53,480 healthy because it is counterintuitive to 1013 00:50:53,480 --> 00:50:55,839 starting to say we're going to go mie en 1014 00:50:55,839 --> 00:50:59,319 not eating it's it's it's it's it's it's it's it's it's it's it's it's it's 1015 00:50:59,319 --> 00:51:01,400 amazing that's what you say 1016 00:51:01,400 --> 00:51:03,000 breathe better if you have apnea 1017 00:51:03,000 --> 00:51:06,240 for a long time it's it's the same 1018 00:51:06,240 --> 00:51:08,880 exit standby principle also for 1019 00:51:08,880 --> 00:51:11,040 winemaker Boivin who settled 1020 00:51:11,040 --> 00:51:14,000 health problems after three courses of 1021 00:51:14,000 --> 00:51:16,280 fast in Germany the French doctor 1022 00:51:16,280 --> 00:51:19,480 regrets the lack of openness of its 1023 00:51:19,480 --> 00:51:21,839 colleagues I tried to convince 1024 00:51:21,839 --> 00:51:24,040 finally to convince people to talk about it 1025 00:51:24,040 --> 00:51:26,280 from me family friends colleagues 1026 00:51:26,280 --> 00:51:27,200 M 1027 00:51:27,200 --> 00:51:30,000 well, anesthetists 1028 00:51:30,000 --> 00:51:31,799 gastroenterologists, surgeons and 1029 00:51:31,799 --> 00:51:36,160 cetera it was a kind of complete Blockout 1030 00:51:36,160 --> 00:51:38,200 it's stupidity it's a sect I 1031 00:51:38,200 --> 00:51:39,240 will lose protein that I 1032 00:51:39,240 --> 00:51:41,440 will never get back what it is 1033 00:51:41,440 --> 00:51:43,760 dangerous et cetera but they themselves have not 1034 00:51:43,760 --> 00:51:46,680 not n didn't try so I stopped 1035 00:51:46,680 --> 00:51:48,880 to try to convince people and then 1036 00:51:48,880 --> 00:51:50,400 when someone is black we throw a 1037 00:51:50,400 --> 00:51:54,599 Bué they take they don't learn 1038 00:51:56,920 --> 00:51:58,760 we're there 1039 00:51:58,760 --> 00:52:01,960 goes to France yet doctors 1040 00:52:01,960 --> 00:52:04,920 they try to move the lines 1041 00:52:04,920 --> 00:52:06,960 do it while walking among others 1042 00:52:06,960 --> 00:52:09,880 Youth 1043 00:52:09,880 --> 00:52:13,040 together they covered 100 km in 5 1044 00:52:13,040 --> 00:52:18,400 days of Montsmichel in SaintMalo without 1045 00:52:19,960 --> 00:52:22,200 eat in stark contrast to 1046 00:52:22,200 --> 00:52:24,480 Germany they face times 1047 00:52:24,480 --> 00:52:27,480 difficult 1048 00:52:28,319 --> 00:52:31,280 in France we have a kind of enormous 1049 00:52:31,280 --> 00:52:33,799 distrust which obviously is based on the 1050 00:52:33,799 --> 00:52:35,799 overflows that there are always in 1051 00:52:35,799 --> 00:52:37,640 all activities there are always 1052 00:52:37,640 --> 00:52:40,599 bandits charlatans 1053 00:52:40,599 --> 00:52:44,040 margoulins who will be able to be pinned 1054 00:52:44,040 --> 00:52:45,599 to give a very bad image 1055 00:52:45,599 --> 00:52:48,000 of a 1056 00:52:48,920 --> 00:52:51,680 practice document practice to 1057 00:52:51,680 --> 00:52:54,839 reassure health authorities train 1058 00:52:54,839 --> 00:52:56,960 doctors to support the game 1059 00:52:56,960 --> 00:52:59,880 as in Germany these are the goals of 1060 00:52:59,880 --> 00:53:02,200 the Medical Academy of Fasting created by 1061 00:53:02,200 --> 00:53:05,040 some doctors 1062 00:53:05,720 --> 00:53:08,000 French when we are interested in 1063 00:53:08,000 --> 00:53:10,280 American international literature 1064 00:53:10,280 --> 00:53:12,799 German English Australian finally 1065 00:53:12,799 --> 00:53:15,440 good a lot in in the English language 1066 00:53:15,440 --> 00:53:18,559 sum of publications it is immense 1067 00:53:18,559 --> 00:53:23,599 and it is completely astonishing that 1068 00:53:23,599 --> 00:53:26,720 doctors who are interested in health 1069 00:53:26,720 --> 00:53:30,240 do not see there the therapeutic treasure which 1070 00:53:30,240 --> 00:53:32,880 maybe is 1071 00:53:32,880 --> 00:53:35,400 explore in a report on 1072 00:53:35,400 --> 00:53:38,000 unconventional care practices 1073 00:53:38,000 --> 00:53:39,400 published in June 1074 00:53:39,400 --> 00:53:42,040 2023 the national council of the order of 1075 00:53:42,040 --> 00:53:43,839 French doctors denounce 1076 00:53:43,839 --> 00:53:46,200 indications assumed by promoters 1077 00:53:46,200 --> 00:53:50,240 of fasting and adds it does not exist to this day 1078 00:53:50,240 --> 00:53:52,000 not enough scientific studies 1079 00:53:52,000 --> 00:53:54,160 numerous and rigorous allowing 1080 00:53:54,160 --> 00:53:55,799 conclude about its effectiveness 1081 00:53:55,799 --> 00:53:58,440 therapeutic 1082 00:54:00,720 --> 00:54:03,559 to simply say there are 1083 00:54:03,559 --> 00:54:05,799 uncertainties trying to kill this area 1084 00:54:05,799 --> 00:54:08,599 research it's serious it only does 1085 00:54:08,599 --> 00:54:11,040 maintain the status qu and maintain a 1086 00:54:11,040 --> 00:54:12,839 very expensive health system which does not 1087 00:54:12,839 --> 00:54:14,119 works 1088 00:54:14,119 --> 00:54:16,760 not in France the health system is 1089 00:54:16,760 --> 00:54:18,760 much better than X United States but it will 1090 00:54:18,760 --> 00:54:20,799 in the same direction you should 1091 00:54:20,799 --> 00:54:22,440 keep in mind that if you continue 1092 00:54:22,440 --> 00:54:24,640 with the drugs you will end 1093 00:54:24,640 --> 00:54:27,960 like the United States 1094 00:54:30,000 --> 00:54:32,880 anyone who claims that the game is 1095 00:54:32,880 --> 00:54:35,440 dangerous or that fasting does not 1096 00:54:35,440 --> 00:54:36,799 of effect 1097 00:54:36,799 --> 00:54:40,720 therapeutic behavior behaves in a manner not 1098 00:54:40,720 --> 00:54:43,520 scientific it is not an attitude 1099 00:54:43,520 --> 00:54:46,520 scientist 1100 00:54:52,000 --> 00:54:57,300 [Music] 1101 00:55:01,119 --> 00:55:03,520 it is perhaps far from France in 1102 00:55:03,520 --> 00:55:05,640 a corner of France at the end of the world 1103 00:55:05,640 --> 00:55:10,240 that a revolution in public health is taking place 1104 00:55:12,910 --> 00:55:25,129 [Music] 1105 00:55:25,319 --> 00:55:27,039 prepare 1106 00:55:27,039 --> 00:55:30,440 bad numbers here at it's 75% of the 1107 00:55:30,440 --> 00:55:33,720 population and overweight and 48% and 1108 00:55:33,720 --> 00:55:35,680 obesity, that is to say half of the 1109 00:55:35,680 --> 00:55:37,319 population is 1110 00:55:37,319 --> 00:55:42,400 obese and 22% suffer from diabetes 1111 00:55:42,400 --> 00:55:45,280 sad records 1112 00:55:46,240 --> 00:55:48,799 planetary it is an evil which strikes 1113 00:55:48,799 --> 00:55:50,440 our youth the youth that we do not 1114 00:55:50,440 --> 00:55:53,440 didn't know before because before well 1115 00:55:53,440 --> 00:55:56,440 we had another way of eating 1116 00:55:56,440 --> 00:55:59,640 it is very good with obesity that 1117 00:55:59,640 --> 00:56:01,839 then it's diabetes then it's 1118 00:56:01,839 --> 00:56:03,839 what is cancer and all the 1119 00:56:03,839 --> 00:56:07,760 complications uh possible and imaginable 1120 00:56:07,760 --> 00:56:10,599 we are affected by everything 1121 00:56:10,599 --> 00:56:13,039 that's why we can't build a country 1122 00:56:13,039 --> 00:56:16,200 with that it's not 1123 00:56:17,920 --> 00:56:21,920 possible how to resist this tsunami 1124 00:56:21,920 --> 00:56:25,280 sanitary it is 4:30 a.m. and in the 1125 00:56:25,280 --> 00:56:26,880 loneliness of the night 1126 00:56:26,880 --> 00:56:29,039 the president of Polynesia fears this 1127 00:56:29,039 --> 00:56:30,359 scenario 1128 00:56:30,359 --> 00:56:32,760 twilight but we say to ourselves that we must 1129 00:56:32,760 --> 00:56:34,359 a start it takes a start of the 1130 00:56:34,359 --> 00:56:35,559 company 1131 00:56:35,559 --> 00:56:38,960 and often it is necessary at the basis of this 1132 00:56:38,960 --> 00:56:40,480 startle a decision 1133 00:56:40,480 --> 00:56:43,079 politics is what we started to 1134 00:56:43,079 --> 00:56:46,039 to do since we were here for 1135 00:56:46,039 --> 00:56:48,760 first time in the world a government has 1136 00:56:48,760 --> 00:56:50,880 includes the game in the policy of 1137 00:56:50,880 --> 00:56:54,039 public health the law was passed in 1138 00:56:54,039 --> 00:56:56,720 unanimity by the territorial assembly of 1139 00:56:56,720 --> 00:57:00,119 Polynesia in August 1140 00:57:00,160 --> 00:57:03,200 2023 using their autonomy in matters 1141 00:57:03,200 --> 00:57:06,079 health the Polynesians are trying to 1142 00:57:06,079 --> 00:57:09,359 regain their health by 1143 00:57:10,680 --> 00:57:14,520 hand we were installed in a system 1144 00:57:14,520 --> 00:57:17,359 of thought where for each illness there is a need for 1145 00:57:17,359 --> 00:57:20,400 medication when in fact the ideal 1146 00:57:20,400 --> 00:57:23,640 would be that we don't get sick and and for 1147 00:57:23,640 --> 00:57:25,839 avoid getting sick fasting is a 1148 00:57:25,839 --> 00:57:27,839 tool it is not the only tool but it is 1149 00:57:27,839 --> 00:57:30,960 an extraordinary tool then obviously 1150 00:57:30,960 --> 00:57:32,880 It’s definitely not very popular. 1151 00:57:32,880 --> 00:57:35,839 with certain lobbies who preferred 1152 00:57:35,839 --> 00:57:37,599 see us consuming ever more to 1153 00:57:37,599 --> 00:57:39,720 get sick so they can sell us 1154 00:57:39,720 --> 00:57:41,839 of 1155 00:57:43,520 --> 00:57:46,559 pills fasting is a component 1156 00:57:46,559 --> 00:57:48,359 which we consider essential in this 1157 00:57:48,359 --> 00:57:51,240 dietary re-education policy 1158 00:57:51,240 --> 00:57:53,960 rehabilitation to the relationship already to 1159 00:57:53,960 --> 00:57:56,960 food 1160 00:57:57,359 --> 00:57:59,760 the political will now registered 1161 00:57:59,760 --> 00:58:02,359 in the law would it be the prelude to a 1162 00:58:02,359 --> 00:58:04,920 individual awareness for a 1163 00:58:04,920 --> 00:58:07,079 return to a more 1164 00:58:07,079 --> 00:58:10,359 healthy the challenge is 1165 00:58:10,359 --> 00:58:12,319 immense 1166 00:58:12,319 --> 00:58:14,960 with the education that was done in 1167 00:58:14,960 --> 00:58:17,839 our country sometimes I have the impression 1168 00:58:17,839 --> 00:58:22,200 that the doctor has become a magician he 1169 00:58:22,200 --> 00:58:24,520 is capable of everything and all that and we 1170 00:58:24,520 --> 00:58:27,480 is in the process of Ch 1171 00:58:27,480 --> 00:58:29,839 this vision to say that the 1172 00:58:29,839 --> 00:58:32,359 the best doctor is your own health 1173 00:58:32,359 --> 00:58:34,960 depends on 1174 00:58:35,090 --> 00:58:38,169 [Music] 1175 00:58:38,240 --> 00:58:41,720 you it's thanks to the young intermittents 1176 00:58:41,720 --> 00:58:43,599 3-day fasts that he practices 1177 00:58:43,599 --> 00:58:45,079 every month and a change 1178 00:58:45,079 --> 00:58:48,440 power supply that Tun pure advisor of the 1179 00:58:48,440 --> 00:58:51,280 Polynesian Minister of Health treated 1180 00:58:51,280 --> 00:58:53,799 type diabetes 1181 00:58:53,799 --> 00:58:58,319 2 years ago he lost 33 kg and is not gaining 1182 00:58:58,319 --> 00:59:00,440 no more 1183 00:59:00,440 --> 00:59:03,520 treatment Tunui has reconnected with the 1184 00:59:03,520 --> 00:59:06,039 frugality of his ancestors these sailors 1185 00:59:06,039 --> 00:59:08,319 extraordinary who crossed the seas 1186 00:59:08,319 --> 00:59:11,359 aboard narrow canoe sometimes short 1187 00:59:11,359 --> 00:59:13,680 of provision at the end of their long 1188 00:59:13,680 --> 00:59:16,680 expeditions 1189 00:59:17,350 --> 01:00:02,640 [Music]